CRO Insights Blog

CSO Observations on Antibody Polyspecificity Screening using Baculovirus Particles: Second in a Series

Tuesday, December 1, 2015

Antibody polyspecificity refers to the ability of an antibody to bind a variety of unrelated antigens and likely explains how  the immune system is able to react with all the antigens that will be encountered in a person’s lifetime [1].

CSO Observations on Trends and Issues in Bioprocess Research and Development: First in a Series

Wednesday, August 12, 2015
A Novel Rhabdo Virus Identified in Sf9 cells. The use of the baculovirus expression system for ...

Considerations for R&D Antibody Production

Thursday, July 16, 2015

 Antibodies constitute the most rapidly growing class of human biotherapeutics, with nearly 50 approved monoclonal antibodies on the market. With a robust pipeline in development as well as derivatives that include single-chain antibodies, chimeric molecules, and antibody conjugates, finding a CRO partner to facilitate early R&D is increasingly a critical best practice to increase flexibility in busy R&D labs.  

Essential Technologies for a Baculovirus Expression CRO

Thursday, June 11, 2015

The baculovirus expression vector system (BEVS) has been an important technology in cell-culture labs around the world for the past 30 years. Its performance parameters include consistent productivity, low-costs, and accessibility have all contributed to its wide adoption. Baculovirus is generally considered safe by biotechnology researchers as it is non-pathogenic to mammals, birds, fish and reptiles...

Should You Outsource Assay Services?

Tuesday, April 21, 2015

The global biotech and pharma contract research organization (CRO) ecosystem is a collection of companies striving to achieve the same goal: to help accelerate the development of new drugs. As a scientist, and potential CRO customer, you want to maximize your R&D efficiency and enhance the quality of your research during early drug development stages. Increasingly, to leverage your time and research budget, a good option is to partner with a domestic CRO...