Phenotypic Drug Discovery

Phenotypic Drug Discovery (PDD) is the process of screening cellular systems rather than specific targets to interrogate biological context with the potential to identify multiple mechanisms and targets simultaneously. The cellular assays used for PDD are more information-rich and the therapeutic relevance of compounds identified is established earlier in the drug discovery process. Modern high content screening technologies, such as the Cellomics CellInsight used at Blue Sky Bioservices, have made PDD possible. The assay options that we offer are flexible and include screens using small molecules, peptides, and RNAi. Our team will guide you through the process of customizing a phenotypic screen to suit your project objectives.